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Simplicity Is Beautiful

My prior post centered on an article in The Atlantic that talked about how upwards of 300,000 people a year die from simple and entirely preventable hospital induced infections or blood clots. This has been tackled by one Dr. Peter Pronovost who established that basic checklists help dramatically. The author of the health reform article was disgusted that his reforms haven’t been adopted widely, and seemed to blame the lack of economic incentive. I said it showed a lack of human decency.

Here is the article he is referring to, as I feel that it’s important enough to warrant its own post.

In 2001, though, a critical-care specialist at Johns Hopkins Hospital named Peter Pronovost decided to give it a try. He didn’t attempt to make the checklist cover everything; he designed it to tackle just one problem, the one that nearly killed Anthony DeFilippo: line infections. On a sheet of plain paper, he plotted out the steps to take in order to avoid infections when putting a line in. Doctors are supposed to (1) wash their hands with soap, (2) clean the patient’s skin with chlorhexidine antiseptic, (3) put sterile drapes over the entire patient, (4) wear a sterile mask, hat, gown, and gloves, and (5) put a sterile dressing over the catheter site once the line is in. Check, check, check, check, check. These steps are no-brainers; they have been known and taught for years. So it seemed silly to make a checklist just for them. Still, Pronovost asked the nurses in his I.C.U. to observe the doctors for a month as they put lines into patients, and record how often they completed each step. In more than a third of patients, they skipped at least one.

Test at Johns Hopkins:

Pronovost and his colleagues monitored what happened for a year afterward. The results were so dramatic that they weren’t sure whether to believe them: the ten-day line-infection rate went from eleven per cent to zero. So they followed patients for fifteen more months. Only two line infections occurred during the entire period. They calculated that, in this one hospital, the checklist had prevented forty-three infections and eight deaths, and saved two million dollars in costs.”

“Pronovost recruited some more colleagues, and they made some more checklists. One aimed to insure that nurses observe patients for pain at least once every four hours and provide timely pain medication. This reduced the likelihood of a patient’s experiencing untreated pain from forty-one per cent to three per cent. They tested a checklist for patients on mechanical ventilation, making sure that, for instance, the head of each patient’s bed was propped up at least thirty degrees so that oral secretions couldn’t go into the windpipe, and antacid medication was given to prevent stomach ulcers. The proportion of patients who didn’t receive the recommended care dropped from seventy per cent to four per cent; the occurrence of pneumonias fell by a quarter; and twenty-one fewer patients died than in the previous year. The researchers found that simply having the doctors and nurses in the I.C.U. make their own checklists for what they thought should be done each day improved the consistency of care to the point that, within a few weeks, the average length of patient stay in intensive care dropped by half.

But there was resistance. Not only was he challenging the professional culture, but this was just one hospital where it was carefully monitored. What about in the real world?

In 2003, however, the Michigan Health and Hospital Association asked Pronovost to try out three of his checklists in Michigan’s I.C.U.s. It would be a huge undertaking. Not only would he have to get the state’s hospitals to use the checklists; he would also have to measure whether doing so made a genuine difference. But at last Pronovost had a chance to establish whether his checklist idea really worked…

Sinai-Grace experienced more line infections than seventy-five per cent of American hospitals…Within the first three months of the project, the infection rate in Michigan’s I.C.U.s decreased by sixty-six per cent. The typical I.C.U.—including the ones at Sinai-Grace Hospital—cut its quarterly infection rate to zero. Michigan’s infection rates fell so low that its average I.C.U. outperformed ninety per cent of I.C.U.s nationwide. In the Keystone Initiative’s first eighteen months, the hospitals saved an estimated hundred and seventy-five million dollars in costs and more than fifteen hundred lives.

And still it hasn’t been widely adopted! Here is a taste of the cultural stuff that I referred to that needs to change:

Something like this is going on in medicine. We have the means to make some of the most complex and dangerous work we do—in surgery, emergency care, and I.C.U. medicine—more effective than we ever thought possible. But the prospect pushes against the traditional culture of medicine, with its central belief that in situations of high risk and complexity what you want is a kind of expert audacity—the right stuff, again. Checklists and standard operating procedures feel like exactly the opposite, and that’s what rankles many people…

“At the current rate, it will never happen,” he said, as monitors beeped in the background. “The fundamental problem with the quality of American medicine is that we’ve failed to view delivery of health care as a science. The tasks of medical science fall into three buckets. One is understanding disease biology. One is finding effective therapies. And one is insuring those therapies are delivered effectively. That third bucket has been almost totally ignored by research funders, government, and academia. It’s viewed as the art of medicine. That’s a mistake, a huge mistake. And from a taxpayer’s perspective it’s outrageous.”..

I asked him how much it would cost for him to do for the whole country what he did for Michigan. About two million dollars, he said, maybe three, mostly for the technical work of signing up hospitals to participate state by state and coördinating a database to track the results. He’s already devised a plan to do it in all of Spain for less.
“We could get I.C.U. checklists in use throughout the United States within two years, if the country wanted it,” he said.

This is why I stated that the reforms need are primarily cultural: if checklists were made and followed for everything then we would save billions upon billions. If the health software was made so it better focused on the actual user needs, we’d save tens of billions. If doctors and patients were more honest about end of life care and people made [personal!!] decisions about what treatment they want based on quality of life, then we’d save hundreds of billions. Ditto if we had more research about what diagnostics/treatments are effective and how to quickly generalize what may be wrong.

None of this will be addressed by either political side, and ultimately they aren’t going to be driven by economics. Yet they are crucial to long term reform and health insurance reform should be viewed as a separate issue.

I must also stress that we cannot afford to wait on these cultural changes. They will take many years to take root and a few decades to become totally commonplace, and one picture summarizes the urgent need (here) to start immediately.

  • GeorgeSorwell
    Mikkel also had an interesting quote in the comments of his other article, about giving nurses the authority to make doctors follow the checklists:
    The next month, he and his team persuaded the hospital administration to authorize nurses to stop doctors if they saw them skipping a step on the checklist; nurses were also to ask them each day whether any lines ought to be removed, so as not to leave them in longer than necessary. This was revolutionary. Nurses have always had their ways of nudging a doctor into doing the right thing, ranging from the gentle reminder (“Um, did you forget to put on your mask, doctor?”) to more forceful methods (I’ve had a nurse bodycheck me when she thought I hadn’t put enough drapes on a patient). But many nurses aren’t sure whether this is their place, or whether a given step is worth a confrontation. (Does it really matter whether a patient’s legs are draped for a line going into the chest?) The new rule made it clear: if doctors didn’t follow every step on the checklist, the nurses would have backup from the administration to intervene.


    And I pointed out of there that the usefulness of proper hygiene was established in the 1840's.
  • CStanley
    I think it's cultural AND economic though.

    You've identified the cultural aspects (I think the doctor/nurse relationship is particularly key- although as the article mentions, some nurses have no problem figuring out how to give those nudges to doctors but by and large there's a reluctance to question them.)

    Economically though, someone has to be accountable for the costs, and that someone has to actually understand what measures would be most cost effective. The article mentioned, for instance, that hospital administrators jumped on the bandwagon of using antibiotic coated lines even though they're costly and don't prevent infections as well as the sterile techniques do. Seems to me that those administrators heard what sounded good (and what was being pressed on them by manufacturers who have a vested economic interest) and went with it instead of having the training to learn what really works.

    Ultimately, no matter how arrogant the doctors are, it's the administrators' responsibility to ensure high quality and efficiency in costs. And if our system held them more accountable for both, the economic pressures would work to push back against the perverse economic pressure of buying ineffective products and the perverse cultural pressure of letting doctors get away with unsafe and costly procedural shortcuts just because no one wants to ruffle their feathers.

    There were a couple of other things in that article worth mentioning IMO. One is that in busy inner city hospital ICUs, the staff is constantly having to shift attention from one emergency to another and understanding this makes it a bit more understandable that people would have trouble with the checklist concept. When you have one critically ill or wounded person that you're trying to make life/death decisions for, and then have to change your focus to a second or third such patient, it would be nearly impossible to stop and mentally review a checklist on the procedures themselves, let alone handle paperwork to document that you've done so. Sometimes, if the choice is between getting a line in quickly or not getting a line in for the patient in the next bed in time, you're going to choose to cut some corners with sterility.

    Also, Provnost made an interesting comment here:
    “The fundamental problem with the quality of American medicine is that we’ve failed to view delivery of health care as a science. The tasks of medical science fall into three buckets. One is understanding disease biology. One is finding effective therapies. And one is insuring those therapies are delivered effectively. That third bucket has been almost totally ignored by research funders, government, and academia. It’s viewed as the art of medicine."

    That's a separate cultural aspect that isn't associated with the arrogance of doctors- it reflects somewhat on their training as well. They recieve lots of training on understanding the diseases, diagnostics, and treatments, but very little on studying how to best deliver those treatments. I would think that would contribute greatly to their reluctance to believe or accept the importance of the checklist system.

    And one final point- I'm not sure that we haven't actually started to address this on a national level. I came across this reference to funding that was enacted earlier this year to healthcare agencies (CDC, NIH, CMS, and others) to implement the recommendations made by the Provnost study nationally. I don't know if it's going far enough or not, or how successful they'll be, but it appears that the 2007 New Yorker article was about a problem that at least is starting to become addressed. Kudos to Obey and other Congressional reps who appear to have gotten the ball rolling at least.
  • CStanley
    GS- I don't think any doctors doubt the effectiveness or flat out necessity of hygiene- it's really more a matter of not having sufficient understanding of how important it is to follow the complete protocol for sterility. It's a lot more than just washing hands- it's cleaning the patient's skin, draping effectively, using sterile dressings to cover the lines, etc. It's all a bit tedious and time consuming, and you have to really appreciate the importance of it or you'll be tempted to cut a step or two out (or, you can also easily be distracted and accidentally do so.)

    Although I did say geez louise when I read the part about how many of the ICUs didn't have Chlorhexidine scrub available. I don't practice veterinary medicine without it- I can't imagine being treated at a hospital critical care ward where the doctors and staff didn't have it available.
  • mikkel
    Haha did you read me say "geez louise" on the other thread? I haven't heard that in years and here I used it and see you in the span of minutes.

    I perhaps was too glib in my generalization about doctors. I do feel that the cultural focus on doctors as wunderkinds or genius specialists that need to be given free reign and have complete obedience by those beneath them leads to a lack of training that has nothing to do with doctor temperament. A lot of times (at least from what I hear from my friends that are nurses) it seems that the formal training about delivery consists of "do what the head nurse tells you, who in turn will be strongly influenced by how the doctors want it." Because it's so informal, the rules are different in every unit and they came to loathe having to cover a shift in another unit simply because they spent their whole time with operational details.

    I do feel that you have a point about the economic incentives and I didn't flesh that thought out clearly. What I meant was that the system has been thoroughly co-opted that business as usual is the way to do things. Thus, I don't believe that mere external pressure will lead to these reforms in particular...they must be targeted directly outside economic channels.

    This is entirely analogous to the financial industry, where there is no institutional memory about things being any different than the way they are now. When the government imposed external measures they were fought against and lending efforts, etc. have been questioned because of the spreads.....when all the government stuff still allowed them to operate more freely and at greater profit than historically!!

    No one (of power) inside the industry has said "hey I bet we can get a leg up if we use this as a chance to make all of these intrinsic reforms," instead they just cut back programs wholesale that they have identified as less profitable or whatever. In the health industry this would cause an outrage and we'd just start pouring more money into it again (education is another perfect example).

    I feel that the carrot of demonstrated efficiency will be more readily pushed through with the economic stick, but I simply meant that the methods won't be developed through economic pressures.
  • CStanley
    LOL- I probably did get the phrase from you but it literally did pop into my head when I read that passage. I find it mind boggling beyond belief that any hospital unit wouldn't have the proper scrub available at all times.
  • shannonlee
    " I don't think any doctors doubt the effectiveness or flat out necessity of hygiene- it's really more a matter of not having sufficient understanding of how important it is to follow the complete protocol for sterility."

    I remember my wife's first day at her new job at a Los Angeles medical center....

    "Oh my god, the doctors and nurses wear their scrubs to lunch...and then they wear them home! This is illegal in my country."

    Researchers are even worse. They work with the really nasty stuff and don't bother wearing lab coats. You also wouldn't believe what gets dumped down a normal sink in some labs.

    We have a lot of cultural problems....sadly, there are other countries that are far far worse in these areas.
  • GeorgeSorwell
    CStanley--

    Sorry to use an improper term.
  • joeinhell
    I had been getting medical care at a VA hospital. The last two times that I was there, I had a surgeon that ignored the six inches of allergies on one inch bands up my right arm and tried to give me a shot of penicillin, the next time the primary care doctor checked my left foot for signs that diabetes was going to get it and then reached up and pulled down my eyelid to check a hard spot that I had been feeling on the soft tissue inside my eyelid. Totally irrationally, unbelievably unsafe and unsanitary bad practices.

    When my appendix burst, I went to a private hospital. Try telling nurses and doctors that you can't breathe, you must have your inhalers (which were NOT prescribed by THEIR doctors), I choked and coughed and tried to open up my airways. Then I got out of bed and within 45 minutes of coming out of anesthesia, I had checked out against doctor's advice (and with a pain medication with acetaminophen in it which I am grossly allergic to and THE DOCTOR refused to change the prescription).and was on a hell flight for 17 hours to where the doctors would listen to me. I was literally shitting blood when I got to Miami. I rolled up a torn up magazine, since it would be totally sanitary, and shoved it up my ass.

    When I got back to my country of residence, I was in the best hospital in the capital within 45 minutes, I had the top teaching physicians for radiology, blood work, surgical work, and parasitology working on me. The nurse was drawing blood as I was going into the MRI. Another nurse helped to get a "stool sample" and almost fainted when I pulled out the magazine and the blood rushed out. She got the doctor immediately. Then I had a CT scan to see something that the MRI did not show clearly. Then they drew blood and ran a second blood examination to see if I had been infected in the us hospital.

    Yes, my wife, her doctor friend and my interpreter were passing out twenty dollar bills by the fistful. Enough that the people in the hospital started saying it was too much. That since I had the courage to fly from the united states to get "their" opinions, that all anyone would take was their regular fee. The controlling physician told me the american doctors had done a good job.

    Yes, they were proud. Yes I went through literal hell, but they listened to my wife and interpreter when they told them what I was allergic to and what they didn't know but I might be allergic to. And no one touched me without washing their hands with alcohol.

    All of this happened after 2 AM. Trying getting top doctors out of bed in the united states at 2 AM.

    As far as I am concerned, the medical system is totally fucked up beyond belief. Skip the damn analysis of everything and simply hire the Swiss to run the medical system. They know how to handle things when the country is run by an oligarchy, just like the US.
  • jagssoftwareguide
    It was a very nice articles guys. Thank you very much.
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